Sentence examples for mutations were targeted from inspiring English sources

The mutations were targeted to amino acids previously demonstrated to be involved in either the intra- or intermolecular salt bridges, thought to be responsible for maintaining the three-dimensional structure of the trimer.

In the second transformation, mutations were targeted 49 and 51 bp from the URA3 site.

Among these, 118 domains from 220 proteins with 3,832 mutations were targeted by viruses.

The mutations were targeted in the inositol oxygenase (inox) and phytoene desaturase (pds) genes using cell suspension culture of wheat and in the pds gene in leaves of Nicotiana benthamiana.

First, in contrast to many other mutation collaboration models, both mutations are targeted to the physiologically relevant endogenous genetic loci.

While most animal models of AD involve ectopic expression or overexpression of FAD-related genes, some pathological features of AD have been recapitulated in mutant and knockin animals in which FAD-causing mutations are targeted into their endogenous genes.

In terms compatible with modern genetics, Lamarck's scheme entails that 1) environmental factors cause genomic (heritable) changes 2) the induced changes (mutations) are targeted to a specific gene(s) 3) the induced changes provide adaptation to the original causative factor.

This was expected, as the mutation was targeted to one of the key residues participating in ligand binding.

KrasG12D mutation was targeted to multiple epithelial tissues via the CK19CreERT [17] and LSL-KrasG12D [18] genetically engineered insertional alleles.

In the first method, site-specific genomic (SSG) mutagenesis, a specific point mutation is targeted into the genome.

Bmi1+ve cells were also able to form small intestinal adenomas when an activating β-catenin mutation was targeted to these cells (Sangiorgi and Capecchi, 2008).