Sentence examples for mutations were set from inspiring English sources

The remaining five sampling years showed signs of bottlenecks in the vast majority of parameter combinations, except when the parameters p s (the fraction of mutations larger than a single step) and Δ g (the mean size of larger mutations) were set at their maximum (see Additional file 3 Table S2).

The overall distribution of mutations is set out in Figure 1.

Recurrent and unstable mutations are set in brackets by Phylotree [4].

A single point mutation was set via site-directed mutagenesis using the primers 5'-CCTAAAAACTGCATGGAGGCACAATATC-3' and 5'- GCAGTTTTTAGGACGACATCTGGCCTTAAAAG-3' leading to the amino acid E(1584)–K substitution on protein level (sequence confirmed by sequencing).

Haplotypes in control individuals were estimated using PHASE, and the relative position of the mutation was set within the haplotype.

Although the threshold for calling a mutation was set to 2%% of base changes, not all base changes above 2%% were called as mutations.

The selection coefficient was set as 0.01, and the frequency of the advantageous mutation was set to range between 10% and 100%, in increments of 10%.

The population size is 100 and the number of generations is 300; 2. The number of hill-climbing iterations for both crossover and mutation is set to 100; 3.

Again, this was due to the fact that 16278T for haplogroup C4a3 was reported as missing in the haplotype even though this mutation was set in brackets in Phylotree.

Mutation rates were set to be constant among loci.

The sensitivity parameters for BRCA1 and BRCA2 mutation screening were set as 70%and80%0% respectively.