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Exact(5)
So far, we only considered sequence reads generated from published genomes, thus no mutations were expected, which could further complicate the mapping of the reads.
When an offspring was produced, mutations (cis- and trans-regulatory mutations) were expected to occur.
Formerly, based on the presumed dominant inheritance mode, only heterozygous mutations were expected.
These mutations were expected to appear within the maternal plasma as rare alleles, like paternal-specific alleles [ 15].
Apart from 4 novel missense mutations (p.P318R, p.G323R, p.I384T, p.Y490N), 73% of the newly described mutations were expected to affect mRNA processing.
Similar(55)
Similarly, the burden of all functional categories is ordered by common expectations as to how often such mutations are expected to be functional.
Partly, this reflects the fact that the mitochondrial gene products are essential for life; that is, most mtDNA mutations are expected to be lethal.
FHM2 mutations predict reduced glial uptake of K+ and glutamate from the synaptic cleft whereas FHM3 mutations are expected to be associated with hyperexcitability of excitatory neurons.
The structural consequences of the two mutations are expected to be distinct [20].
A buffering effect of deleterious mutations is expected if epistasis would be positive.
These mutations are expected to be selected by AZT, and perhaps by other NRTI, particularly thymidine analogues.
Related(20)
moves were expected
mutations were predicted
deployments were expected
mutations were suggested
deployment were expected
mutations were hitherto
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mutations were detected
mutations were eliminated
mutations were verified
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mutations were made
mutations were observed
mutations were confirmed
mutations were created
mutations were predictive
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