Sentence examples for mutations that characterize from inspiring English sources

These are a few of the answers we received: Male, 24, Law student: "Evolution is a consecutive passage of phases or mutations that characterize a species from its appearance on Earth until its complete disappearance, on the basis of empirical and environmental data and experiences.

This presumably reflects the "oncogenic" transformation of the cancer cell lines relative to normal cells, events that reflect the multiple mutations that characterize cancer cells.

Exome or whole-genome deep sequencing of tumor DNA along with paired normal DNA can potentially provide a detailed picture of the somatic mutations that characterize the tumor.

Of the many mutations that characterize myeloid malignancies, some (TET2, ASXL1) can initiate a preleukemic clone, whereas others (MPL, JAK2) are phenotypic lesions that trigger the overt malignant disease (Vainchenker et al. 2011).

While considerable efforts have been made to identify the mutations that characterize this disorder, pathogenesis remains a work in progress with less than 100 patients described in current literature.

For example, estrogen receptor negative and estrogen receptor positive breast cancer are different in terms of the somatic mutations that characterize them, as well as with regard to natural history and responsiveness to treatment.

Specifically, we identified a de novo GRIN2A mutation that characterized the increased activity of NMDARs with which it was incorporated, and showed that memantine inhibited this hyperactivity in vitro.

Genotyping of the Hmx1 dm and wild-type Hmx1 (Hmx1 +) alleles was performed by real-time PCR using oligonucleotide primers having 3′ termini at the point mutation that characterizes the dmbo mutation, as previously described (Quina et al., 2012).

Our informatics methods can augment research into the molecular basis of disease, using data from decades of studies to identify similarities in somatic mutation patterns that characterize similar cancer types.

The structure of the MBD mCpG complex clearly rationalizes some MBD point mutations linked to the dysfunctions that characterize Rett syndrome.

Founder mutations are those that are present in all samples analyzed for a patient; from an evolutionary perspective, founder mutations are those clonal events that characterize the 'most recent common ancestor' of all cells in the neoplasm, or the parental clone that gave rise to it.