Sentence examples for mutations suppress the from inspiring English sources

In addition, daf-16 mutations suppress the FIRE-response resistance of daf-2 mutants under nutrient deprivation (Fig. 2C) [8].

However, in contrast to autonomous-pathway mutants, brm mutations suppress the low levels of expression of FLC of SWR1 complex mutants.

It remains to be studied why daf-16 mutations suppress the enhanced resistance to P. aeruginosa-mediated killing of glp-1 only when bacterial lawns are grown under certain conditions [19].

We have found that animals heterozygous for ico missense mutations suppress the overproliferation and pattern defects caused by expression of a constitutively activated form of the DPP type I receptor TKV in wings.

As daf-18 mutations suppress the lifespan phenotype of daf-2 and age-1 mutants, it has been proposed that the role of DAF-18 in lifespan regulation relies on inhibition of the insulin/IGF-1 signaling pathway (Mihaylova et al., 1999).

10.7554/eLife.05118.007 Figure 4. RAB-3 GAP mutations suppress the snt-1 mutant phenotype.

The strength of selection for new driver mutations determined whether a mutator phenotype would evolve; very strong or very weak selection for driver mutations suppressed the evolution of a mutator phenotype (Fig. S3A).

Strong negative clonal selection against deleterious housekeeper mutations suppressed the evolution of a mutator phenotype (Fig. S3B).

Within the model, cancers evolve with a mutator phenotype when driver mutations bestow only moderate increases in fitness: very strong or weak selection for driver mutations suppresses the evolution of a mutator phenotype.

Cancers were more likely to have evolved a mutator phenotype when selection for additional driver mutations was moderate s d ∼0.01; strong selection for additional driver mutations suppressed the evolution of a mutator phenotype (Fig. 4A).

In this process there is a potential selective pressure for secondary mutations suppressing the most severe manifestation of the phenotype.