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Mutations supply the fuel that fires the evolutionary machinery.
Mutations supply the genetic variation for adaptation, but their success depends on the selective coefficient (s), which influences both the probability of fixation of a mutation and its frequency trajectory [ 1].
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Although beneficial mutations are much rarer compared to deleterious mutations, they supply the driving force for adaptive evolution and contribute to survival of populations in tough environments [ 39].
Retreives a feature list for all mutations supplied by the user.
As a result of differences in mutational supply, the strength of selection and the relative costs of resistance mutations, different levels of resource supply select for qualitatively different bacterial resistance mutations, and correspondingly, phage infectivity mutations (Forde et al., 2008; Lopez Pascuaa et al., 2012).
Thus Mayr, in a piece [ 48] entitled "The Resistance to Darwinism and the Misconceptions on which it was Based", writes: Those authors who thought that mutations alone supplied the variability on which selection can act, often called natural selection a chance theory.
The architects of the MS stressed that mutation is the ultimate source of variation, but it is not a proximate cause of evolution (i.e., evolution does not begin with a new mutation), nor an effective agent of change: "mutation merely supplies the gene pool with genetic variation; it is selection that induces evolutionary change" (p. 613 of [ 23]; for further documentation of this view, see [ 34]).
B) Please supply the individual mutation numbers in a table format with raw numbers so that the reader can determine the actual numbers that the % represents.
Although in some cases the absolute rate of adaptation is more strongly limited by the recombination rate than the mutation supply or the strength of selection, for example [ 79], the relative rates of adaptation are still determined largely by the product of x i and x j.
The mutation supply and the minority lineages in figures 4 and 5 provide the genetic potential for further evolution as well as the maintenance of heterogeneity during the later phases of this experiment.
As a consequence, high mutation supply in the repeat domain is ensured due to the high total copy number of repeats.
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