Sentence examples for mutations counteract the from inspiring English sources

Glu112 in combination with other mutations present in XG-34/2-I (Val32 → Glu, Val80 → Ile, His110 → Gln, Gln119 → Leu, Thr129 → Ala) did not however result in an improved affinity, suggesting that one or several of these other mutations counteract the contribution in affinity for xyloglucan promoted by Glu112.

The constrained mutations decreased the stability of the nucleoprotein at high temperatures, while the enabling mutations counteracted this effect.

Changes in gene frequencies due to mutation occur, therefore, at rates even slower than was suggested above, because forward and backward mutations counteract each other.

These results suggested that progeny viruses from the MAMM mutant might contain adaptive mutation(s) to counteract the inhibitory effect of the NA inhibitor.

If the mean effects of deleterious mutations was too small to counteract the beneficial mutation effects (e.g., s d ¯ is smaller than 0.01), the optimum mutation rate might reach a higher value than the one presented.

It also brings up crucial questions for future research: Scientists still don't know how particular mutations cause cancer, why they lead to cancer in some tissues and not others, or what might be done to counteract the mutations.

The genetic relationship between nuclear-encoded proteins and mitochondrial proteins/rRNAs is asymmetric (Rand et al. 2004; Osada and Akashi 2012; Barreto and Burton 2013) in the sense that compensatory mutations in the former continue to counteract the effects of deleterious mutations in the latter.

It is possible that the previous studies used very low pH (pH 5.6) such that POA-resistant mutants could not survive the combined lethal action of low pH and POA because the level of resistance conferred by target mutations such as PanD mutations may be too low to counteract the combined action of POA and acidic pH.

THO and TREX2 mutations per se do not counteract the inhibitory effects caused by HU because the single-deletion mutants are sensitive to high HU concentrations and are synthetic sick in combination with rad53 (data not shown; Gómez-González et al., 2009).

Since the mutations did not reduce the annealing activity as they did the helicase, the mutant proteins might actively counteract the unwinding of a substrate.

However, drugs to counteract the effect of genetic mutations have not yet been found.