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Exact(6)
Asp96Asn alone resulted in a 1.8-fold improvement in phage display efficiency, but in combination with the cysteine replacing mutations, a total of 130-fold improvement in phage display efficiency of DHPS was achieved.
In addition to these mutations, a total of four different synonymous single nucleotide polymorphisms (SNPs) were identified in BRAF (Table 1), MEK1 (Table 2), and MEK2 (Table 3).
Following on from those initial mutations, a total of 44 different MAPT mutations have been reported (http://www.molgen.ua.ac.be/).ua.ac.be/
In addition to the putative pathological mutations, a total of 24 GALC polymorphisms were identified within either the exons, introns or 5′ untranslated region (5′ UTR).
To test for linkage of tgr1 with sequenced mutations, a total of 36 tgr1 BTG-active individuals were analyzed with SSR markers tightly linked to cloned genes associated with epigenetic gene regulation in maize, mop1, mop2, rmr1, and rmr6.
Interestingly, at least 500 mutational catalogs with an average of 96 mutations per catalog (a total of ∼50,000 mutations) are needed to decipher five mutational processes, but these five mutational processes can be more easily deciphered from 50 cancer genomes containing an average of 480 mutations (a total of ∼25,000 mutations, Figure 3D).
Similar(54)
In families without a demonstrable BRCA mutation, a total of 3,161 healthy women aged 25 59 years were prospectively followed for 24,808 observation years.
Nevertheless, since the A2063T transversion mutation must be related to more profound damage to growth efficiency, the reason remains unknown why so many strains with the rarely reported A2063T mutation, a total of 27, were isolated in this study (in the Fukuoka area).
Eleven out of 20 (55%) tumors harbored somatic mtDNA mutations with a total of 14 mutations.
In contrast, only 23% of non-smokers possessed mutations with a total of 10 point mutations and no insertions/deletions detected.
In contrast, only 23% (7/30) of non-smokers possessed mutations with a total of 10 point mutations and no deletions/insertions.
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