Sentence examples for mutation was most from inspiring English sources

However, drug-resistance patterns were largely similar to those in subtype B. Resistance profiles were associated with the antiretroviral drugs commonly used: the lamivudine-associated M184V mutation was most common, followed by K103N which is associated with non-nucleoside reverse transcriptase inhibitors.

Interestingly, the BRAFV600E mutation was most prevalent within the ganglioglioma subtype of pediatric LGAs (classical and non-classical; 8/14 tumors, p = 0.00005), as shown in Fig. 2. BRAFV600E mutations were not identified in any of the adult tumors examined, although TP53 mutations commonly occurred in this setting (10/28 cases).

Previous investigations of the effects of the E1-A226V mutation on CHIKV infection of midguts, dissemination into salivary glands, and transmission to a vertebrate host by Ae. albopictus suggested that the epidemiologic success of CHIKV with the E1-A226V mutation was most likely due to enhanced midgut infectivity [9], [10].

The appearance of this mutation was most frequent amongst MDR strains [ 15].

Mutation was most frequently found in tetranucleotide and trinucleotide repeats with only a low proportion of alterations in dinucleotide repeats.

In non-muscle-invasive tumours where mutation was most frequent, mutations in the promoter of telomerase (TERT) (>80%) (9, 10) and activating mutations in FGFR3 (∼70%) (11) are the most common events recorded to date.

(B) Cell lines with both BRAFV600E and RAS mutation were most susceptible to increased FDG uptake.

It has been reported that PTEN is a gene in which mutation is most frequently found in primary breast cancers [11].

These previous results had suggested that individuals carrying this mutation were most likely related.

The relative large portion of patients without a mutation is most likely due to clinical misdiagnosis.

In general, theoretical studies indicate that intermediate levels of mutation are most favorable for adaptation (Orr 2000b).