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The R306C mutation proved most useful for understanding the function of the less well-studied MeCP2 C-terminus.
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Mutation of His194 to threonine proved most significant, with a switch in specificity from NADH to NADPH [ kcat/Km NADH /kcat/Km NADPH) from 1.5 1 to 1 3.5, mostly as a result of a reduced Km for NADPH of approximately sevenfold in the His194Thr mutant.
"Indie" and "electronic" proved most popular.
Four consecutive burst pulses proved most effective.
The interviews and FGDs proved most informative.
Within the Bacteria domain, the Firmicutes phylum proved most abundant.
An Arg16 to norvaline mutation proved suitable.
Since the late 1990s, there's been enormous interest in harnessing leptin as a weight-loss drug, but so far, it's proven most effective for a small number of people who have a mutation in the leptin receptor gene.
And what solutions prove most effective?
Which have proven most popular?
The two major subdivisions prove most relevant to understanding FTD.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com