Sentence examples for mutation is comparable from inspiring English sources

Plasma cells from subjects with active SLE manifest extensively mutated VH and VL genes, and the pattern of mutation is comparable to that noted following T cell-dependent antigen stimulation [ 14- 17, 44- 468]68].

The output of this study also will provide information in the identification of genes mutated due to EMS mutagenesis and demonstrate the distribution of mutation is comparable in different germplasm of MG-20.

The autistic-like behaviour caused by SLC9A6 mutation is comparable with that of Rett and Angelman syndromes.

The occurrence of this mutation is comparable to that found in Polish [ 22, 23, 25, 42] and Russian [ 20] populations, but significantly higher than that described in Germany [ 43] and Austria [ 21].

The proportionally large size of the NKX2-5YRDY−A C-set alsuggestssthathathisis mutation is comparable in severity to NKX2-5Y191C, supporthegeneticevidencevidElliottlliott et al., 2006).

Therefore, we also aimed to assess the degree of neuroanatomical variability within each of the genetic mutations and sporadic FTD, in order to determine whether variability in the new C9ORF72 gene mutation is comparable with the other groups.

The relative levels of cell proliferation within growth plates of mice heterozygous for the mutation were comparable to those of the wild-type mice (data not shown).

Study on malignant progression of low-grade astrocytomas to high-grade tumours revealed that the frequencies of TP53 mutation were comparable in both groups of tumours, suggesting that TP53 mutation is an early event in the evolution of diffuse astrocytoma (Watanabe et al, 1997).

As the probability of a cell acquiring a deleterious mutation was comparable to that of the cell acquiring an advantageous mutation, negative clonal selection impeded the growth of only rare cells within the most aggressive clone, and so failed to impede tumour growth.

Further, Russo et al. have reported that the developmental pattern of breast tissue from parous women with a family history of breast cancer or BRCA1 mutation was comparable to that from nulliparous women with no family history (that is, did not differentiate with parity) [ 24].

The growth plates of mice heterozygous for the mutation were comparable to those of wild-type mice in that they had an organized growth plate with clear proliferative and hypertrophic zones and a regular vascular invasion front, however, some regions of hypocellularity were observed within the proliferative zone indicating an intermediate phenotype (data not shown).