Sentence examples for mutation is consistent from inspiring English sources

The lethality of homozygotes for the K519A mutation is consistent with the growth defect of the OsIRE1 KD line (Supplementary Fig. S2).

The enhanced skeletal muscle glycogen deposition demonstrated in carriers of the analogous γ3 mutation is consistent with the above results in the heart.

The striking similarity to the classical FOP mutation is consistent with the current disease model suggesting that FOP results from increased kinase activity [11].

We find p16 mutations can occur very early during neoplastic progression in BE, and the spectrum of mutation is consistent with that of oxidative damage that can be generated as a result of chronic reflux.

The marked increase in INaL caused by the mutation is consistent with mutant Na+ channel activity that can contribute to delayed repolarization of cellular action potentials[12], but this is not the only biophysical property altered by the mutation that might contribute to the disease phenotype.

Thus, the observed low frequency of mutation is consistent with only a subtle transcriptome difference between OSCR11 and a123.

Our observations on the KCNQ1 P320H mutation are consistent with previous studies indicating that pore mutations in potassium channel α-subunits are associated with more severe electrophysiological and clinical phenotypes than mutations in other regions of these proteins.

These stimulatory effects of BMPRII and ACTRIIB mutation were consistent with the results obtained from transient gene expression experiments in the absence of BMP7 suggesting that wild type BMPRII as well as ACTRIIB receptors were involved in mediating a negative regulation of telomerase activity.

In humans, strong evidence supporting the presence of genetic modifiers of iron metabolism was reported by Whitfield and colleagues who studied a sample of both monozygotic and dizygotic twin pairs and showed that the pattern of residual variation in serum iron indices, after adjusting for an effect of the C282Y mutation, was consistent with the additive effects of multiple genes [19].

The reduced abnormalities and laminin binding ability of α-dystroglycan in fish co-injected with the human L276I mutation are consistent with human relatively mild clinical finding course.

Our results for the R798X mutation are consistent with a moderate risk of PrCa, comparable to that for breast cancer, but larger numbers will be required to confirm this.