Sentence examples for mutation is frequent from inspiring English sources

TP53 deletion or mutation is frequent in B-cell malignancies and is associated with a low response rate.

Mitochondrial mutation is frequent in salivary ACCs.

The CEA mutation is frequent in the Collie lineage, but occurs at only low frequency in the Border Collie breed in France (Chaudieu, personal communication).

Amino acid site mutation is frequent, with the accumulation of mutations potentially contributing to the functional divergence of duplicated genes [ 30, 80, 86, 87].

In addition, this type of mutation is frequent, particularly in the MSH2 gene, implying that the mutation screening algorithm should begin with MLPA and not with DNA sequencing, especially in cases where the protein expression pattern of the tumor shows a loss of MSH2 protein or is unknown.

The G595A mutation was frequent already in the first generation progenies, while, in all the late progenies, small deletions in this region were found, with Δ596-598 being predominant (Fig. 4A and Data S1).

Oncogenic activation by mutations of the CTNNB1 (3) and PIK3CA (4) genes and amplification of the ERBB2 (5) gene, and inactivation of the CDH1 (6) and TP53 (7) tumor-suppressor genes by mutation, are frequent in gastric carcinomas.

This work also demonstrates that while the introduction of mutations is frequent, the rate of substitution over longer time periods is many fold lower, in part due to purifying selection acting on nonsynonymous mutations.

BRAF mutations are frequent in melanoma but their prognostic significance remains unclear.

(2015) demonstrate that passenger mutations are frequent in most genetically engineered congenic mice and persist even after extensive backcrossing.

We tested the hypothesis that these mutations were frequent in cancer genes, by studying again TP53.