Sentence examples for mutation and expression from inspiring English sources

Several studies have focused on the mutation and expression landscapes of HCC and ICC.

When the domain composition of a target is poorly understood, or if there are insufficient structure data to guide sited directed mutagenesis, long iterative phases of subcloning or mutation and expression often prove unsuccessful despite much effort.

The field of molecular biology studies macromolecules and the macromolecular mechanisms found in living things, such as the molecular nature of the gene and its mechanisms of gene replication, mutation, and expression.

Conceptual and methodological frameworks from each of these disciplinary strands united in the ultimate determination of the double helical structure of DNA (conceived of as an informational molecule) along with the mechanisms of gene replication, mutation, and expression.

This grouping was concordant with comparable 4-way cluster structure recently reported by the TCGA.[26] Integration of copy number aberration, mutation and expression of EGFR, PDGFRA and NF1 revealed that three of the transcriptomal classes were enriched for alterations in each gene, respectively, although the segregation was imperfect.

Particularly, we enhance an integrative model which combines gene mutation and expression data.

In 10,522 cancer genomes from The Cancer Genome Atlas, aneuploidy was correlated with TP53 mutation, somatic mutation rate, and expression of proliferation genes.

The subgenomic promoter was inactivated with 13 synonymous mutations and expression of the EEEV structural proteins was placed under the control of an internal ribosomal entry site (IRES) derived from encephalomyocarditis virus (EMCV).

Although specific K-Ras mutations and expression of oncogenic H-Ras are rarely detected in non-neoplastic Barrett's epithelium, both of these abnormalities are found frequently in dysplastic Barrett's epithelium and in esophageal adenocarcinomas [21] [25].

These changes include gene amplifications, mutations and expression alterations.

Accordingly, mutations and expression analyses demonstrated distinct molecular signatures associated with mutations of specific functional domains.