Sentence examples for mutants we studied from inspiring English sources

Interestingly, the dramatic decrease of NIR activity in the different mutants we studied was the result of higher KM and lower kcat values compared to those of WT APE1.

Given the ABA hypersensitivity of wrky2 mutants, we studied the effect of ABA on the early development of wrky2 mutants.

To determine whether the different modulating effect of PKA was specific to COX mutants we studied three additional mtDNA mutations.

Using these add-back mutants, we studied the contributions of the tyrosine sites to tumorigenesis and lung metastasis in transgenic mice.

In contrast, we observed no change in dyskerin·hTR complex formation for the autosomal dominant DC hTR mutants we studied [G309T, C408G, and G450A], suggesting that such mutations probably act via a distinct mechanism at the molecular level.

Measuring the ratio of cell surface mutant Pen-2 to that found in the lysate input and then normalizing to the ratio for wild-type Pen-2 revealed that among the four mutants we studied in stable cell lines, only N33A showed a significant increase in the proportion of cell surface Pen-2 to total cellular Pen-2.

Taken together, these observations show that the P-element insertion mutants we study cause a reduced expression of the Hsp83 gene in three different genetic backgrounds.

With these observations in mind, we asked whether the natural Hsp90 mutants we study here are impaired in their ability to buffer cryptic variation that can be revealed by inbreeding.

Since several of the mutants that we studied (Table S1) have been described only partially or not at all, we decided to establish a phenotypic description for all the mutants in order to confer a common framework for the interpretation of the transcriptome results.

To investigate whether the decreased complex activities cause increased ROS production or increased ROS inhibits the complex activities in the dOpa1+/− mutant files, we studied their mitochondrial aconitase activity.

Because the FBP28 mutant that we studied was designed to eliminate aggregation, we would not expect to observe this phase.