Sentence examples for mutant that retains from inspiring English sources

Whereas neither the hma2 nor the hma4 mutant has an easily visible growth phenotype, the hma2 hma4 double mutant is severely stunted (even in the Ws mutant that retains a full-length version of HMA3), and this phenotype is rescued by application of Zn [12].

This finding was also important because it showed that removing vinculin does not enhance every talin mutant that retains partial activity.

Importantly, the phosphatase activity of Fig4p is required for its regulatory function; an active site mutant that retains interaction with Vac14p is nonetheless defective in elevation of PI 3,5 P2 levels (Bonangelino et al, 1997; Duex et al, 2006b).

Similarly, p53, a p53 mutant that retains the ability to induce senescence, but not p53-mediated cell-cycle arrest and apoptosis, still inhibited KrasG12D-induced lung carcinogenesis (Brady et al., 2011).

To improve the ability to resolve these two subcomplexes, we used a B. subtilis mutant that retains thick septal peptidoglycan because it lacks the mother cell transcription factor (σE) that controls septal thinning, the first step in engulfment.

Many but not all spermathecal protein mRNAs, including many that are likely to be involved in sperm maintenance, are greatly reduced in an Hr39 mutant that retains spermathecae (Allen and Spradling, 2008).

Furthermore, even if it were possible to produce a cysteine mutant that retained activity, the poor efficiency of polymer conjugation to the thiol group made it impossible to obtain the desired product.

This was recently challenged by a study of an α-toxin mutant that retained full virulence in a chicken NE model [ 7].

This latter point arises because we note that every talin mutant that retained partial activity in the wing can make a talin dimer/monomer with two IBSs: Δhead still has the dimerization helix and so can make a homodimer with two IBS2s, whereas deletion of ABD results in a monomer containing IBS1 and IBS2.

To facilitate genome-wide functional analysis in S. pombe, we generated a barcode-tagged S. pombe library of random insertion mutants that retains features equivalent to the budding and fission yeast ORF deletion mutant collections, enables identification of mutants in the absence of knowing the barcode sequences, and allows parallel analysis with basic molecular biology techniques.

The autonomous pathway was originally defined by late-flowering mutants that retain a photoperiod and a vernalization response [29].