Sentence examples for mutant background where from inspiring English sources

Indeed, Mafb was capable of restoring synapses even in the Gata3 mutant background, where SGN development is severely disrupted.

Localization of each of the fusion proteins was also determined in a ΔtssE mutant background, where absence of the essential baseplate component TssE results in an inactive T6SS.

However, in that case it is unclear why the effect of atocd is the same in wild type and the p5cs1-4 mutant background where total proline synthesis is much less.

To tackle this question, we analyzed the expression dynamics of the peptidases genes influenced by Lp WJL association in a mutant background where the host transcriptomic response to the microbial environment is impaired, namely in Dredd mutants.

Thus, one could speculate that the efficacy of Notch localization and signaling may be attenuated in a baz mutant background, where the systems regulating polarity are highly sensitized, therefore resulting in mild PFC multilayering.

This approach is possible as the FTL crossover reporter system was generated in the qrt1-2 mutant background, where sister pollen grains remain physically attached as meiotic tetrads (Berchowitz and Copenhaver, 2008).

We combined an smn heterozygous mutant background with either mutant backgrounds (where available) and/or with over-expression constructs of random genes out of our lists.

ypIn2 pot-1:: mCherry was placed into the pot-2 mutant background analogously, where ypIn2 pot-1:: mCherry unc-52 hermaphrodites were crossed to rol-6 / +; pot-2 / unc-52 males and phenotypically wildtype F2 progeny were selected.

Although depletion of PHB does not affect the lifespan of the glyoxylate mutant gei-7 (our unpublished observation) it would be interesting to see if gei-7 is required in the mutant genetic backgrounds where PHB elimination extends lifespan.

To test this hypothesis we performed microarray experiments with either treated or untreated AX2 wt cells (wt; experiment I), the STATc knock-out mutant (STATc-, experIIInt III) and a mutant with an isogenic background where the STATc knock-out construct was randomly integrated into the genome (RIC, experiment II) (Table 3).

The existence of this dynamic regulatory role is further confirmed by the interesting phenotype of motion in the PA66 background, where the mutant form of the protein allows a dramatic change in droplet motion between phase II and IIb, but the subsequent down-regulation of transport expected between phase IIB and III fails to occur.