Sentence examples for mutant background suggests from inspiring English sources

Furthermore, the smaller 4-fold effect of the G41V mutation in the D38E mutant background suggests that Gly41 helps to position the general base.

The stronger effect of the phx1 mutation in the Δsck2 mutant background suggests that in the absence of the Tor kinase, Phx1 may contribute more to cell survival than in the absence of protein kinase A. Constitutive activation of the Sty1 MAP kinase pathway of S. pombe has also been reported to extend chronological lifespan [ 6].

However, in A. thaliana these responses were observed only in nim1/npr1 mutant background, suggesting that the NPR1 protein suppresses the plant responses to Rhizobium.

Furthermore, the effect of D-CblL-mPR over-expression was not suppressed in the heterozygous drkEOA mutant background, suggesting that PR of D-CblL might be a critical binding domain for Drk (Table 1).

The incidence of tumors increased in a p53 mutant background, suggesting that the p53 pathway suppresses EWS-FLI1-driven tumorigenesis.

Magnetic-induced calcium responses in AFD were not observed in a tax-4 mutant background, suggesting that this requires Ca2+ entering the TAX-4 cGMP-gated ion channel.

In contrast, expression of an AXR3::GUS reporter was down-regulated in a pax1-1 mutant background suggesting that in wild-type plants, PAX1 regulates AXR3 transcription positively.

Therefore, because DRONC is inactive in ark mutant background suggesting that the cleaved-Caspase-3 labeling signal is not caused by the unknown DRONC substrate, this analysis demonstrates that the cleaved-Caspase-3 antibody does indeed detect cleaved DCP-1.

However, the severe 35S::ZRP3-induced leaf phenotype is ameliorated in the wrky53 mutant background, suggesting that the action of other HD-ZIPIIIs involves WRKY53 also at early stages (supplementary material Fig. S7).

We confirmed that the Eiv phenotype was induced by RNAi of acs-4 alone in the wild-type background at a lower frequency than the cdk-8 RNAi in the rnt-1 mutant background, suggesting that acs-4 is not the only target gene.

The cell-plate-localized proteins RAB-A2a fused to yellow fluorescent protein (YFP-RAB-A2a) as well as DYNAMIN-RELATED PROTEIN1A (DRP1A -GFP (also known as ADL1A-GFP; Kang et al, 2003) did not display the lateral mis-localization observed for KNOLLE in the cpi1-1 mutant background, suggesting some specificity of this effect to KNOLLE.