Sentence examples for mutant strain where from inspiring English sources

We thus tested the GRC efficiency in a lig4Δ mutant strain where non-homologous end joining activity is deficient [10].

Recently, our group performed a study on the replicative capacities of the A/Brisbane/59/2007 H275Y mutant strain where we showed that its fitness, based on in vitro and animal studies, was similar to that of its wild-type (WT), oseltamivir-susceptible, counterpart [22].

As observed for the wild-type strain, all the mutant strains were non mucoid indicating no increase in exopolysaccharides synthesis except for the opgH mutant strain where mucoidy was increased indicating an increase in exopolysaccharides synthesis.

In a motA mutant strain, where the flagella are unable to rotate, the mesh of flagella filaments were seen to be less entangled, suggesting that flagella rotation is required for effective tethering together of the cells and enables the formation of the mesh of flagella filaments at the base of the macrocolony (Serra et al. 2013b).

pmt mutant strains where constructed transforming the JEC20/21 derivatives JEC155 (MATα, ade2 ura5), JEC156 (MATa, ade2 ura5), or F99, respectively, a 5-FOA resistant derivative of H99.

This tendency is likely to be due to the need to conserve female mice for breeding particularly in mutant strains where fecundity is an issue.

This is supported by experimental data indicating a basal expression of csgB in mutant strains where the EAL domain was mutated to an AAL domain, thus diminishing the binding affinity of c-di-GMP to YciR [ 7].

There exists an upper bound to the functioning of the dosage compensation mechanism: in triple qrr mutant strains where qrr4 is among the deleted qrr genes, whereas the remaining qrr gene is upregulated, its promoter is not activated strongly enough to completely compensate for the lack of the other three qrr genes.

The results reveal altered intergenic Pol II transcription near TFIIIC binding sites in the mutant strains, where we observe readthrough of upstream transcripts that normally terminate near these sites, 5′- and 3′-extended transcripts, and de-repression of adjacent genes and intergenic regions.

Here, we devised a new approach and engineered a single mutant mouse strain where the endogenous Ctgf-3' untranslated region (3'UTR) was replaced with a cassette containing two 3'UTR sequences arranged in tandem.

In general it requires analysis of embryogenesis of mutant mouse strains where regular arrangement of sensory hair cells in the inner ear and neural tube closure phenotypes are the most commonly used readouts for PCP-like signaling in mammals [ 7, 8].