Sentence examples for multiple pathophysiological pathways from inspiring English sources

Multiple pathophysiological pathways are involved in the relationship between depressive symptoms and atherosclerosis and its clinical manifestations and progression.

There is compelling evidence that blood coagulation and tumor biology are connected through multiple pathophysiological pathways.

Further studies should simultaneously tackle multiple pathophysiological pathways, and long-term functional outcomes shall be assessed by means of outcome measures able to recognise subtle cognitive changes.

PLE is a serious complication in a subset of patients with Fontan circulation It is unclear what triggers the development of PLE and why it can develop so long after Fontan surgery PLE may be the common endpoint of multiple pathophysiological pathways.

The AHRR gene, known as a tumor repressor (Zudaire et al. 2008), codes a protein involved in multiple pathophysiological pathways, such as metabolism of tobacco smoke components (Kasai et al. 2006; Moennikes et al. 2004) and regulation of cell proliferation and differentiation (Haarmann-Stemmann et al. 2007; Pot 2012).

Using a quasi-experimental opportunity offered by greatly restricted air pollution emissions during the Beijing Olympics compared to before and after the Olympics, we conducted the current study to compare ultrafine particles (UFPs) and fine particles (PM2.5) in their associations with biomarkers reflecting multiple pathophysiological pathways linking exposure and cardiorespiratory events.

It is now evident that AMPK may modulate multiple physiological and pathophysiological pathways including enhancement of eNOS activity by phosphorylation [ 15– 17].

Therapies may need to target multiple sites in the pathophysiological pathways of AKI and MODS in order to be of any benefit for patients.

The improved performance of this model compared with that of single markers demonstrates the value of risk assessment models that incorporate multiple biomarkers from diverse pathophysiological pathways associated with type 2 diabetes.

Research prospects for new biomarkers of TBI should focus on demonstration of functionality in converging pathways that can impact multiple pathophysiological cascades.

In the context of disease research and drug discovery, our disease AOP concept would provide a unified framework for describing relevant pathophysiological pathways and networks across multiple biological levels and for encompassing extrinsic and intrinsic causes.