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The transcriptional mechanism mediating MST1 gene expression is still not well understood, especially under multiple pathophysiological conditions.
The application of these analytical techniques has led to the concept that RLS (reactive lipid species) are mediators, not simply by-products, of multiple pathophysiological conditions [ 8– 11].
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The constitutive activation of NF-κB contributes to multiple cellular outcomes and pathophysiological conditions such as rheumatoid arthritis, asthma, inflammatory bowel disease, AIDS and cancer.
The constitutive activation of NF-κB contributes to multiple cellular outcomes and pathophysiological conditions such as rheumatoid arthritis, asthma, inflammatory bowel disease [ 3], AIDS [ 4] and cancer [ 5].
Abnormal NO signalling contributes to a diverse range of pathophysiological conditions, including the degenerative pathologies of multiple sclerosis, Alzheimer's disease and Parkinson's disease (Steinert et al., 2010).
Dietary flavonoids possess a multiplicity of neuroprotective actions in various central nervous pathophysiological conditions including depression.
Chronic nicotine exposure has been shown to affect multiple transporter systems at the BBB and in brain in physiological and pathophysiological conditions.
However, studying a single ASD candidate gene at a time is not likely to provide a comprehensive explanation of all pathophysiological conditions associated with these disorders, which are believed to result from dysregulation of multiple genes.
Our present knowledge on the multiple pathophysiological mechanisms involved in SWS, KTS, and the PPV does not allow us to determine whether these rare conditions should be included among the phakomatoses.
In addition, obesity is implicated in multiple pathophysiological complications such as T2D and cardiovascular disease (CVD 4,5,6.
There are various pathophysiological conditions that affect the cytoskeletal architecture.
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