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In addition, assay platforms such as ELISPOT, chromium (Cr51) lysis and proliferation (CFSE dilution or H3-thymidine uptake) have a limited capacity to measure multiple immune functions.
Secreted adipsin and visfatin have multiple immune functions as most other adipokines [ 63].
DC-SIGN is a transmembrane lectin receptor on dendritic cells (DC), which can recognize many pathogens and modulate multiple immune functions (Zhou et al. 2006).
As far as the second network is concerned, it is worth mentioning that NOTCH1 and ETS1 have been implicated in multiple immune functions.
Given down-regulation of multiple immune functions and processes involved in tissue repair, stress can augment vulnerability of fish to wounding and infections.
The relationship between genetic merit and health is not well determined, but a recent study of multiple immune functions in lactating cows suggested association among immune traits with health events and fitness of dairy cows [ 3, 4].
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Early efforts to profile multiple immune effector functions of single immune cell function used ICS FFC.
The products of the pleiotropic IL-4 gene intervene in multiple immune modulating functions depending on a variety of cell types [ 9].
One suggested mechanism is the production of short chain fatty acids (SCFAs), which have multiple metabolic and immune functions.
This treatment may help improve T-lymphocyte subset distribution and improve the host's immune functions, but multiple cycles are necessary for long-term therapeutic efficacy.
Copper deficiency impacts innate and acquired immune responses, suggesting that copper is likely to regulate the functions of multiple immune cell types [ 109].
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