Sentence examples for multiple immune mediators from inspiring English sources

Upon removal of Treg, CD8+ T cell polyfunctionality increased in the post-vaccine samples with a greater number of the CD8+ T cells secreting multiple immune mediators.

Although there was no significant change in CD8+ T cell polyfunctional response after vaccination, Treg depletion increased the polyfunctionality of the total vaccine response (P = 0.029), with a >2-fold increase in the percentage of CD8+ T cells producing multiple immune mediators.

This is because studies have shown that an effective immune response against HIV is characterized by the ability of CD8+ T cells to produce multiple immune mediators: IFNγ, interleukin-2 (IL2), TNFα, macrophage inflammatory protein 1β MIP-1β), and the cytotoxic degranulation molecule CD107a.

First, it comprises a comprehensive measurement of multiple immune mediators regulated independently from each other.

The quantitative determination of IFN-γ, TNF-α, IL-2, IL-8, MIP-1α, MIP-1β, RANTES and IP-10 concentrations in urine was performed using a human CBA Flex Set, a flow cytometry application that allows for simultaneous quantification of multiple immune mediators.

These authors demonstrated elevated expression of multiple innate and adaptive immune mediators consistent with tissue injury response, Th1-type T cell response, and suppression of counterregulatory pathways.

We did not adjust for multiple testing because our outcomes and the immune mediators investigated were not independent of each other, so Bonferroni correction would have been too conservative.

To account for imbalances between both groups, the association of immune mediators with foot ulcer was assessed in multiple linear regression models (Table 3 ).

More elegant and highly specific medicines have been designed to target certain immune mediators of the adaptive immune system.

We hypothesized that immune mediators in urine may serve as biomarkers for bladder cancer (BCa).

We investigated differences between singleton and twin gestations in immune mediators in midtrimester amniotic fluid.