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The ability to incorporate multiple functional sites into a single system enhances the interest seen in MOFs.
Concerning tunable porosity, multiple functional sites and devisable host guest interactions, goal-directed designs lead to task-specific MOFs and are requisite to perform precise molecular recognition in liquid-phase adsorption/separation.
These data imply that there are multiple functional sites along the gene through which genetic variation could effect WNK1 expression and function.
This novel dendrimeric nanocarrier with multiple functional sites has tremendous potential as drug delivery vehicle.
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For example, the interval between the two splice site signals MDN-IR and MA1-IR represents a retained intron between an upstream exon with multiple functional donor sites and a downstream exon with multiple functional acceptor sites.
More than 50% of human transcripts have multiple functional polyA sites, and the specific use of alternative polyA sites (APA) results in isoforms with variable 3′-untranslated regions, thus potentially affecting gene regulation.
The presence of multiple functional SUMOylation sites (SUMO consensus sequence = ψ KXE/D, where ψ is a hydrophobic amino acid, X is any amino acid, and K is the specific SUMOylation target) within PPARγ has been confirmed [ 14, 27], and Floyd and colleagues [ 27] describe multiply SUMOylated forms of PPARγ.
However, when multiple target or functional sites within that particular system are attacked by different mechanisms (i.e., multiple chemical exposures or chemical exposures combined with other risk factors), the system may no longer be able to homeostatically reregulate itself, thereby leading to sustained or cumulative damage.
Signaling proteins contain multiple functional components and multiple sites of post-translational modification.
The raw data provided by KEGG were used to extract gene pairs with one or multiple protein domains, families or functional sites in common.
MFS comparison across a multiple sequence alignment revealed five functional sites conserved between Hmd enzymes and paralogs.
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