Sentence examples for many functional sites from inspiring English sources

The Mics of cyanobacteria were shown to be different from Sco7700, Sgr1269, Scab5041, Ndas2620, and Snas1991 at many functional sites, but was highly homologous to Caci4612, which is a putative 2-MIB synthase of Catenulispora acidiphila DSM 44928.

Conservation is commonly used as a filter to identify likely targets, but many functional sites are not conserved and many conserved sites do not seem to be functional [50], [60].

We expect that the gold standard is missing some, and possibly many, functional sites.

Merely setting a high cut-off on peak height to reduce noise [ 51] will therefore risk losing many functional sites.

The promoter region of this gene contains many functional sites including a multiple response element (-173 to -145), which is responsive to interleukin-1, tumour necrosis factor-α, nuclear factor-κB (NFκ-B) and glucocorticoids [ 6].

Many functional sites in the genome undergo transitions in DNA methylation during cellular differentiation and are thought to modulate regulatory interactions and transcription (Mohn and Schübeler 2009; Ong and Corces 2011).

The scan took about one day to complete on 13 parallel processors, suggesting that a large-scale scan of many structures with many functional site models is actually quite efficient.

This is illustrated by the fact that typical mammalian pre-mRNAs harbor many pseudosplice sites that fit the consensus splice site sequences, but which are normally not used [ Sun and Chasin, 2000], and conversely, many functional splice sites do not conform well to the consensus splice site sequences.

They have many reactive functional sites and binding pockets per molecule, and their globular shape and large size makes them easier to filter than linear polymers.

In principle, SeqFEATURE can be applied to build models for other sequence-oriented motif databases, such as Pfam or PRINTS [ 36], to generate many more functional site models quickly and automatically, greatly increasing FEATURE's coverage of protein function space.

The failure of computational methods to find many functional non-canonical sites cannot rule out the possibility that many of these sites might still exist; if such sites are recognized through unimagined determinants, computational efforts might have missed them.