Sentence examples for multiple epigenetic mechanisms from inspiring English sources

In this study, we report that the CDKN1C is repressed in breast cancer by multiple epigenetic mechanisms.

Our comprehensive epigenetic analysis of these observations highlights the emerging concept that multiple epigenetic mechanisms collaborate to repress gene expression in cancer cells.

Albeit the current picture remains incomplete, the view emerges that multiple epigenetic mechanisms cooperate for repressing critical developmental regulators.

Increasing the number of studies focusing on multiple epigenetic mechanisms will strengthen the understanding of environmentally induced alterations to the epigenome.

Our findings suggest that marsupials use multiple epigenetic mechanisms for imprinting and support the concept that lineage-specific selective forces can produce sets of imprinted genes that differ between metatherian and eutherian lines.

Recent work in human non-Hodgkin lymphoma (nHL), the group of diseases most similar to canine lymphoma, has identified multiple epigenetic mechanisms that could affect phenotype, aggressiveness, and response to therapy [ 8- 10].

Transposase-mediated transposition may play a role in the multiple genetic and epigenetic mechanisms that together contribute to aphid phenotypic criteria and might act in concert to maximize host adaptation to unfavorable environmental conditions.

Over the past years, it has become apparent that this 'one gene, one outcome' hypothesis is an oversimplification of the multiple genetic and epigenetic mechanisms that account for ovarian cancer survival.

Recently, multiple reports have linked epigenetic mechanisms to the phenotypic effects of environmental exposures during critical periods of development (Anway et al. 2005).

While most nuclear lncRNAs control multiple cellular processes through epigenetic mechanisms, a number of them also exert their function post-transcriptionally by regulating alternative splicing (Fig.  1, mechanism 2) [ 88].

In summary, our findings provide multiple lines of evidence that epigenetic mechanisms are involved in the regulation of miR-200c/141 expression in both normal and cancer cells.