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This is mainly due to the cooperation and redundancy of the multiple epigenetic signals (DNA and histone modifications), as well as to the transcriptional activity of each particular gene [ 121], which can reinforce the preservation of the current state.
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Epigenetic signals conceal some of these selves and reveal others, coiling some, uncoiling others.
Ishidate, T. et al. ZNFX-1 functions within perinuclear nuage to balance epigenetic signals.
Not surprisingly, multiple epigenetic modulators can regulate expression of Wnt pathway constituents44.
Yao, S. et al. Retrovirus silencing, variegation, extinction, and memory are controlled by a dynamic interplay of multiple epigenetic modifications.
In conclusion, ART manipulations may have important influences on multiple epigenetic biomarkers.
1) Developing new technologies to rapidly assess the role of multiple epigenetic modifications in T cell function.
Uncoupling of genomic and epigenetic signals in the maintenance and inheritance of heterochromatin domains in fission yeast.
They looked for epigenetic signals on the genes signals that tell the body to "turn on" these genes.
The vast array of epigenetic signals whereby genes are switched on or off ensures a steady flow of two-way communication between the genome and its wider environments.
Our comprehensive epigenetic analysis of these observations highlights the emerging concept that multiple epigenetic mechanisms collaborate to repress gene expression in cancer cells.
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