Sentence examples for multiple epigenetic agents from inspiring English sources

This unique biological feature has specific therapeutic implications for the clinical treatment of these tumors, as multiple epigenetic agents, such as DNMT inhibitors and HDAC inhibitors, are currently being developed, with some already being approved by the U.S. Food & Drug Administration FDAA) in clinical trials [54], [55].

Not surprisingly, multiple epigenetic modulators can regulate expression of Wnt pathway constituents44.

Yao, S. et al. Retrovirus silencing, variegation, extinction, and memory are controlled by a dynamic interplay of multiple epigenetic modifications.

In conclusion, ART manipulations may have important influences on multiple epigenetic biomarkers.

We investigated if random epigenetic alterations promoted the cold hardiness of Ae. albopictus eggs from a transgenerational study of two epigenetic agents (genistein and vinclozolin).

1) Developing new technologies to rapidly assess the role of multiple epigenetic modifications in T cell function.

These epigenetic agents also reduced the number of cultured metastatic RMS14 cells (Figure 5C).

Our comprehensive epigenetic analysis of these observations highlights the emerging concept that multiple epigenetic mechanisms collaborate to repress gene expression in cancer cells.

Since these genes are likely to be undergoing epigenetic deregulation, they represent rational targets for therapeutic intervention with epigenetic agents.

A most recent method, jMOSAiC [ 20], jointly analyzes multiple epigenetic features in multiple samples.

This combination of three epigenetic agents shows remarkable anti-leukemic activity against leukemic cells.