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Asthma exhibits multiple clinical presentations in child- and adulthood, of which the pathogenesis and curative therapies remain to be discovered.
Celiac disease (CD) is a difficult-to-diagnose condition because of its multiple clinical presentations and symptoms shared with other diseases.
Further, these properties of the RPGRIP1 interactome underpin likely the multiple clinical presentations of disease mutations impairing its components.
This action may also apply to familial prion diseases where a single mutant allele is capable of producing multiple clinical presentations.
Indeed, previous studies have reported a high prevalence of parasitism within the donkey population in Ethiopia [ 1, 9]. 'Loss of body condition' in a donkey is not necessarily pathognomonic for helminthiasis and it was acknowledged by participants that the same plant based preparations were often used for multiple clinical presentations.
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Some patients were assigned to multiple clinical presentation groups.
After passing through this autoantigenic bottleneck, the initial humoral autoimmune response then usually diversifies, with the sequential development of autoantibodies binding multiple specificities before clinical presentation and diagnosis.
Although there are multiple possible explanations for the variable clinical presentations of the reported patients including hypomorphic expression of HOIL-1 or effects of mutations on protein function, another possibility was that environmental factors alter the clinical presentation of HOIL-1 deficiency.
The presence of multiple comorbid conditions may contribute to varied clinical presentations and poor outcomes in hemodialysis (HD -dependent patients witHD -dependentice infection.
Relapse may occur at single or multiple sites and there is a diverse range of clinical presentations according to the size and location of relapse.
They included fever, multiple painful oral ulcers, disseminated umbilicated papular skin lesions over the face, body and extremities, and multiple swollen, warm, and tender joints which are typical clinical presentations of disseminated P. marneffei infection.
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