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To explore the value of multiple clinical endpoints in the unique setting of ovarian cancer.
Results were correlated with multiple clinical endpoints: disease control, objective response, and progression-free survival (PFS).
Further, it incorporates both a relatively large number of KRAS wt patients and multiple clinical endpoints.
Several studies have evaluated multiple clinical endpoints, but the approach taken in integrating results across these multiple endpoints has varied.
The one-sided OLS statistic is the most widely used global test for the analysis of multiple clinical endpoints [ 27].
Robust linear regression models were used to test for the association of combined biomarker panels with multiple clinical endpoints.
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To illustrate evaluation of multiple, correlated clinical endpoints for evidence of efficacy and for dose selection, a permutation method was applied retrospectively.
The present study aims to provide a comprehensive assessment of vaccine safety and efficacy against multiple virological and clinical endpoints using the techniques of systematic review and meta-analysis.
Multiple imputation uses multiple predictions of missing clinical endpoints based on patient characteristics and the baseline value of the clinical outcome variables [ 16].
Although it is logical that definitive evaluation of new therapies should be based on clinically meaningful outcomes, there are major difficulties to overcome when conducting treatment trials in multiple sclerosis (MS) with clinical endpoints such as relapse rate or progression in disability.
The ITT cohort was preserved by imputing missing clinical endpoints using a multiple imputation procedure that minimizes bias from differential drop-outs and properly accounts for uncertainty in imputed values when performing statistical inference.
More suggestions(15)
various clinical endpoints
several clinical endpoints
many clinical endpoints
multiple pharmacodynamic endpoints
multiple correlated endpoints
multiple clinical indications
multiple collaborative endpoints
multiple primary endpoints
multiple hierarchical endpoints
multiple clinical sites
multiple noncanonical endpoints
multiple clinical areas
multiple clinical entities
multiple clinical uses
multiple secondary endpoints
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CEO of Professional Science Editing for Scientists @ prosciediting.com