Johnson's death occurred at the same time that the F.D.A. was analyzing a large set of data compiled from multiple clinical trials.
Multiple clinical trials have shown that cardiac stents are no more effective than drugs or lifestyle changes in preventing heart attacks or death.
"It's a drug that's been studied in multiple clinical trials in various indications," says Dr. Howard Hutchinson, AstraZeneca's chief medical officer.
Currently, and in spite of multiple clinical trials, thrombolysis remains as the only approved therapy.
As experience with multiple clinical trials accumulates, some general concepts seem worth emphasizing.
Multiple clinical trials have demonstrated β-blockers improving survival after myocardial infarction (MI).
Since then, multiple clinical trials have proven BoNT-A to be an effective therapy for refractory OAB [2].
IGF1R specific kinase inhibitors have failed in multiple clinical trials partly because of the complex nature of IGF1R signaling.
While data are still emerging, the results from multiple clinical trials can best be described as mixed.
Vascular (VBT) has clearly been shown in multiple clinical trials to decrease restenosis rates for in-stent restenosis (ISR).
Multiple clinical trials have been conducted to determine the outcome of stem cell transplantation on cardiac function.
