Sentence examples for mouse model represents from inspiring English sources

A humanized mouse model represents a valuable means of assessing human immune responses to diseases such as cancer.

Thus, this mouse model represents a suitable tool to investigate the molecular mechanisms leading to epigenetic reprogramming.

This mouse model represents a useful tool for further mapping of proximal and distal regulatory elements in rodent BDNF gene in vivo.

Our novel T-ALL mouse model represents an important new tool for better understanding the molecular targets of HMGA2 in T cells, uncovering signaling pathways in which HMGA2 participates, and for testing potential anti-T-ALL drugs.

Since this expression pattern is similar to that described with PDA patients, 14 15 this mouse model represents a tractable experimental platform to interrogate the interaction of SPARC and nab-paclitaxel.

Despite this limitation, the CCL2 transgenic mouse model represents a good experimental system in which leukocytes accumulate in the perivascular space, and parenchymal infiltration can be stimulated using PTx.

The approach used in this study to evaluate psoriasis mouse models represents a general strategy that can be applied to score alternative mouse phenotypes with resemblance to specific human diseases.

The use of pre-clinical mouse models represents a common approach exploited to validate laboratory observations in vivo.

In conclusion, these mouse models represent valuable experimental paradigms for human pathogenesis.

To test the potential in vivo significance of the above observations, we investigated the effect of WFA on STS growth, local recurrence, and metastasis using several human STS xenograft mouse models representing different complex karyotype STS histological subtypes.

Mouse models represent powerful tools for gene discovery in human disease.