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APP23 mouse model is known to have relatively slow plaque deposition and large Aβ deposits with dense amyloid cores [4],[4]].
Still, Studer notes that the mouse model is a simplified version of Parkinson's disease, so the challenges in treating human patients with therapeutic cloning are still large.
But here's the problem -- each mouse "model" is different and no single mouse "model" shows all the pathologic features of AD.
The corresponding mouse model is Rab27aash mice [20].
Aortic imaging in a transgenic hyperlipidemic mouse model is an alternative [8].
Modulation of pro-inflammatory cytokines in ICD mouse model is shown in Figure 4A.
The pathogenesis of bi-cytopenia in this mouse model is likely multifactorial.
Among these, the Mecp2-null mouse model is widely accepted [13] [16].
Like NPC1 mice, the NPC2 mouse model is also on a uniform background [BALB/c; 10].
Our mouse model is similar to another TLX1-T-ALL mouse model described in the recent De Keersmaecker study [44].
The mouse model is the most widely used to experimentally manipulate candidate genes for ASD susceptibility [30].
