Sentence examples for mouse model provides from inspiring English sources

Altogether, the proposed ER+/ERαKD tumor-bearing mouse model provides a promising preclinical platform to investigate novel ER-specific therapies using PET imaging.

In summary, this mouse model provides important insights into CLC development and suggests inhibition of phosphatidylinositol 3-kinase (PI3K) signaling as a potential therapeutic strategy for targeting CLC.

Although 10-fold greater quantities of antibody are required to observe significant effects in mouse, compared to our previous studies in rats, the present mouse model provides a convenient paradigm for investigating catalytic and non-catalytic antibodies.

The mouse model provides the most relevant setting to study and molecularly dissect the process of metastasis in vivo.

Collectively, these findings suggest that our mouse model provides an important experimental platform for probing the underlying mechanisms responsible for this unique disease.

The Snord116 mouse model provides a novel system to study the mechanism of hyperphagic behavior, and to test potential therapeutic interventions.

Small-molecule drugs that help to fold and process proteins correct type 2 diabetes in a mouse model, providing a new lead for the treatment of human diabetes.

In conclusion, this study demonstrates that bioluminescent N. meningitidis strains together with the CD46 transgenic mouse model provide a potent tool for in vivo investigations of meningococcal disease.

The human SKOV-3 cell xenograft mouse model provided the opportunity to evaluate species differences in the effort to classify cancer-associated proteome as either tumor-derived (human) vs. host response (mouse).

Taken together, our results confirm the important role for TLR2 signaling in diet and/or bacteria enhanced atherosclerosis in an ApoE+/− mouse model, providing a link between innate immunity, inflammation and atherosclerosis.

We demonstrated that a single intranasal, but not intramuscular, vaccination with AdAg85A in a mouse model provided a level of protection against pulmonary M.tb challenge that was comparable to or even better than that by standard s.c BCG vaccination [10].