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The thapsigargin-sensitive ER Ca2+ content in the crt−/− mouse fibroblasts expressing AtCRT3m was very similar to the thapsigargin sensitive ER Ca2+ storage capacity of the AtCRT3 expressing cells (Figure 5G).

Further as mentioned before, eIF2α was found to suppress transformation, since NIH3T3 mouse fibroblasts expressing a Ser-51 to Ala mutant of eIF2α become transformed and tumorigenic in vivo [22].

While studying the effects of sFRP-3 on mouse fibroblasts expressing Wnt-1, we noticed that sFRP-3 also inhibited proliferation of control fibroblasts that do not express Wnt-1 or any other Wnts at significant levels.

To address this question, we tested whether treatment with the phytochemicals stimulated shedding of TGFα from mouse fibroblasts expressing ADAM17.

In parallel, we performed experiments with mouse fibroblasts expressing transcriptional or translational clock gene::luciferase (per2:luc or PER2::LUC) reporters.

The murine mAb 806 was generated following the immunisation of mice with NR6 mouse fibroblasts expressing the de2-7 EGFR (Jungbluth et al, 2003).

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We report here that human epithelial cells, including lung cancer cells, like mouse fibroblasts, express a non-coding RNA from the intergenic region of the rRNA gene, and that a negative regulatory role is possibly implied, since there was a negative correlation between levels of the nc-rRNA and total rRNA in most of the human lung adenocarcinoma cell lines studied.

Mouse fibroblasts express low, but detectable, levels of Sox2 (Eminli et al., 2008), and therefore, we wondered whether p27 deficiency affected Sox2 expression.

To examine their utility in vivo, either AVE-1642 conjugates were intravenously delivered to mice bearing xenograft tumours of mouse embryo fibroblasts expressing human IGF1R or MCF-7 human breast cancer cells.

Phosphorylation of EphB4 was assessed in mouse embryonic fibroblasts expressing human EphB4.

We previously performed tandem affinity purification (TAP) of protein complexes from Tiam1−/− mouse embryonic fibroblasts expressing TAP-tagged TIAM1 (Mack et al., 2012).

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