Sentence examples for mouse lines expressing from inspiring English sources
In the present study, we constructed a recombinant MHV-68 expressing Cre and screened a variety of mouse lines expressing a Cre-activatable reporter gene for expression of the reporter following infection.
By contrast, mouse lines expressing single isoforms of wild-type human tau do not produce tau filaments or show neurodegeneration7,8.
The full power of conditional mutant mice can therefore only be exploited with the availability of well characterized mouse lines expressing Cre-recombinase in tissue, organ and cell type-specific patterns, to allow the creation of somatic mutations in defined genes.
Mouse oocytes were injected with the construct, and three mouse lines expressing the transgene were obtained.
More than 120 different SOD1 mutations have been identified (http://alsod.iop.kcl.ac.uk/als), and several transgenic mouse lines expressing disease causative SOD1 mutants have been generated and thoroughly characterized [23].
Recently, two transgenic mouse lines expressing TCRs specific for two defined TAAs have been developed in order to analyse how TAA expression in normal tissues affects T cell function.
In addition, this phenotype was observed in another transgenic mouse line expressing NANOS2-ZM (line #4), although expression of the transgene was restricted to a fraction of the male gonocytes in this line (supplementary material Fig. S1B D).
To further define the role of 5-HT1A receptor-expressing neurons, we generated a transgenic mouse line expressing Cre recombinase in these cells.
To investigate, we generated a transgenic wild-type mouse line expressing AQP1 in the fiber cells using αA-crystallin promoter.
We performed patch-clamp recordings from interneurons near the border of stratum radiatum (SR) and stratum lacunosum-moleculare (SLM) in hippocampal area CA1 in a mouse line expressing green fluorescent protein (GFP) under the neuropeptide Y (NPY) promoter (hereafter NPY interneurons).
A mouse line expressing mitochondrial Dendra2 (mito-Dendra2) has been generated to study mitochondrial dynamics in primary tissue (Pham et al. 2012).
