Sentence examples for more restricted binding from inspiring English sources

In contrast, OdH1t, the shortest linker histone, lacks the conserved phosphorylation motif, suggesting a more restricted binding affinity range.

In contrast, the MSL complex shows more restricted binding in ESCs, which expands after differentiation, particularly at NPC-specific genes.

In contrast to the extended binding pattern of hnRNP C, U2AF65 displays more restricted binding, with a strong preference for the regions directly upstream of 3′ splice sites.

LM19 bound to primary cell walls, whereas LM20 had a more restricted binding pattern to the middle lamellae and intercellular space linings; conversely to what is generally observed in angiosperm parenchyma [ 31].

The crystal structures of GTF-180 and GTF-SI (Vujičić-Žagar et al. 2010; Ito et al. 2011) show that part of this loop delineates the active site; a longer loop at this position thus may result in a more restricted binding cleft in 4,6-αGTs.

This more restricted binding pattern could be due to the activity of other chromatin-binding modules, including the N-terminal AT hooks of MLL1 which have been demonstrated to bind AT-rich regions of DNA [ 67] and a PHD finger (PHD3) which may recognize specific histone methylation marks [ 68– 71].

Noxa is known to be poorly apoptotic in some cell types, and compared with other BH3-only proteins, Noxa demonstrates tethered potential for neutralization of pro-survival Bcl-2 proteins, with a more restricted role binding only Mcl-1 and A1.

The distribution of TypeII (PACAP/VIP) binding sites is more restricted than that of typeI binding sites, and are located in the olfactory bulb, the cerebral cortex, the dentate gyrus of the hippocampus, thalamus, the locus coeruleus of the pons, area postrema, and the spinal cord [46 50].

The work in this study is focused on what the authors refer to as the 'extreme sets' of p53 binding sites: ~2 million predicted p53 binding sites genome-wide, for which there is no experimental evidence of actual binding or regulatory function, and a far more restricted set of ~160 response elements with experimentally characterized binding and regulatory activities.

Peptide binding to CLR/RAMP3 involved a more restricted range of residues than that to CLR/RAMP1 or CLR/RAMP2.

If a less restricted model does not show improved fit over a more restricted one, then the more parsimonious restricted model is the appropriate one.