Sentence examples for more physiological insulin from inspiring English sources

We confirmed and extended these findings in LRP5-KD primary SVCs treated with a more physiological insulin dose (10 nM).

Compared with injections, insulin pump therapy can provide more physiological insulin dosing and lower the need for insulin (37, 39).

Since insulin is secreted into the portal circulation, this approach has the advantage of more physiological insulin delivery and reduced peripheral hyperinsulinemia.

After subcutaneous injection, insulin aspart is absorbed faster and eliminated more quickly than human insulin, thus it has a more physiological insulin profile [ 10].

LY2605541 may therefore have the potential to restore a more physiological insulin action and reduce the peripheral hyperinsulinemic action typical of exogenous insulin therapy.

63 Typically in the US, insulin is injected with a syringe and vial, and there are two main modes of administration, ie, multiple daily injection, where patients inject a fixed amount of insulin, and continuous subcutaneous insulin injection, which allows for incremental insulin administration and more physiological insulin delivery.

Long-acting insulin analogs have been developed to produce a more physiological basal insulin action than seen with such human insulin preparations as neutral protamine Hagedorn (NPH) insulin, and they are associated with lower hypoglycemia rates (particularly nocturnal) while achieving similar glycemic control (10– 10).

Rapid-acting insulin analogues are commonly selected for insulin pump therapies to achieve more physiological postprandial insulin levels.

To truly mimic the cephalic response, insulin analogs are needed that are more rapidly absorbed in order to establish more physiological plasma insulin levels postprandially without leading to increased insulin levels preprandially.

This reflexive behavior of ordering sliding scale may be harmful, comparing unfavorably to the more physiological scheduled insulin therapy.

Consequently, a more physiological meal insulin substitution may decrease immediate postprandial hyperglycemia, whereas the more rapid tapering of hyperinsulinemia may reduce the risk of late postprandial hypoglycemia.