Sentence examples for more physiological relevance from inspiring English sources

To gain more physiological relevance, we introduce cancer cell migration between lattices as a perturbation to the system.

This event could have more physiological relevance when ER Ca2+ homeostasis is being restored after stress by Ca2+ removal from the cytosol.

Thus, we next used a TPO-dependent, GATA-1-null megakaryocyte cell line, G1ME cells, to test the function of PSTPIP2 in megakaryocyte differentiation under more physiological relevance.

The reviewers suggest additional experiments to help with this: for example, some are to add more in vivo physiological relevance, some are for more control experiments, and some are to add more stainings with other markers besides GFAP to show that the cells really are astrocytes.

This observation demonstrates the importance of Arg89, Glu93, and Arg139 in binding the unknown ligand and, more importantly, the physiological relevance of the unknown ligand in affecting EPS production.

Likewise, although the presence of leptin receptors in these glial cells was reported more than a decade ago (20), their physiological relevance remains to be elucidated.

Despite the fact that HDL endocytosis has been known for more than 40 years, its physiological relevance is still under debate.

Furthermore, to ensure that phosphorylation of PDCD4 has relevance in a more physiological context, the levels of PDCD4 phosphorylation were examined in CLL cells that had been cultured with NLCs compared to those without NLCs.

Also the fact that the increased expression of thermogenic and browning genes in Bmp8b TG mice occurred early in the post-weaning phase, when mice are more vulnerable to low temperatures, suggested the physiological relevance of BMP8b mediating the adaptation to cold demands.

Some sites are identified that are very poorly conserved where cleavage is more likely to be fortuitous than of physiological relevance.

Unquestionably much more work is required to elucidate the physiological relevance of duplicate sbPAC1 and alternative approaches such as ligand mutational studies; gene knock-down strategies and physiological experiments will be needed.