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The definition of the molecular subgroups based on IHC is given in Table 3.
The 203 tumors fell into one of five molecular subgroups based on IHC criteria described above (Table 1).
ER- breast cancer can be divided into different molecular subgroups based on the expression microarray profiling [ 2- 4].
Also, it is well established that this neoplasia has well-defined molecular subgroups based on gene expression profiling closely related to the behavior of these molecular subtypes.
These results suggest that establishment of molecular subgroups based on KRAS and BRAF mutation status is important and should be considered in future prognostic studies in CRC.
Our results suggest that establishment of molecular subgroups based on KRAS and BRAF mutation status is important and should be considered in future prognostic studies in CRC.
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We created a second molecular subgroup based on recent evidence that only about 25% of animal S. aureus isolates carry the scn gene, whereas human isolates carry it about 90% of the time (Sung et al. 2008; Verkaik et al. 2011).
We applied immunohistochemistry molecular characteristic subgroups based on previous reports [ 22, 23].
Thus, stratifying patients by molecular tumor subgroups based on RNA profiles could potentially facilitate the identification of new breast cancer susceptibility genes by increasing the statistical power of linkage analysis, genome-wide association, or exome sequencing studies.
Later, the Bordeaux group divided HCAs into four different subgroups based on molecular genetics, histopathology and clinical features.
Because of their elevated response to chemotherapy (CHT) and their ability to be divided into prognostic subgroups based on molecular biology, this group of tumors has generated substantial interest over the past decade.
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cellular subgroups based
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molecular phylogenies based
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molecular subgroups rooted
molecular mechanisms based
molecular methods based
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molecular phenotypes based
molecular analyses based
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molecular models based
molecular assays based
molecular masses based
molecular mechanics based
molecular simulations based
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