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These results confirm the notion that specific molecular mechanisms, based on sequence context and chromatin configuration, are involved in the regulation of drug-induced DNA demethylation.
and to more efficiently identify underlying molecular mechanisms based on biological interpretation of results.
These results are highly suggestive of convergent molecular mechanisms based on protein interactions independently selected during the evolution of viruses.
Genetic studies point to molecular mechanisms based in highly conserved controllers of periodicity or Zeitgaber (13, 14).
The observed size distribution of circular molecules suggests that they are most likely generated by molecular mechanisms based on homologous recombination requiring long stretches of sequence similarity.
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We propose a model for this molecular mechanism based on the results presented here.
A similar molecular mechanism, based on the function of the leading candidate gene, was investigated for the QTL qSTA4-1, whash has the largest effect.
Group I introns code for ribozymes (catalytic RNAs) that perform self-splicing by a common molecular mechanism based on a series of transesterification reactions [ 25].
Previously, we identified a molecular mechanism, based on "fitness fingerprints" displayed on cell membranes, which allows direct fitness comparison among cells in Drosophila.
Weitao et al. review the structural and functional characteristics of viral and cellular SOS-regulated motor proteins with a focus on the relationship of translocation mechanism to motor function, while Costa et al. discuss the dissolvasome machinery in double Holliday junction dissolution and its molecular mechanism based on the structural interplay between its components.
Molecular recognition mechanisms based on multivalent receptor ligand interactions can offer dramatically higher affinity and specificity in comparison to monovalent binding.
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