Sentence examples for molecular structure we from inspiring English sources

In search of new compounds with strong antiproliferative activity and simple molecular structure, we designed a novel series of agents based on the 2-amino-3-alkoxycarbonyl/cyano-5-arylethylthiophene scaffold.

According to the molecular structure, we used 22 PAA groups in our charge calculations.

Because GAGs and heparin share a similar molecular structure, we investigated how HA and other GAGs affect antithrombin activity.

Since ziv-aflibercept and aflibercept have similar molecular structure, we decided to test ziv-aflibercept at similar concentrations as aflibercept.

6 Since ziv-aflibercept and aflibercept have an identical molecular structure, we decided to test ziv-aflibercept (0.125 mg) which has a reduced concentration compared with aflibercept (2 mg).

To confirm the stability of the molecular structures, we carry out simulations in explicit solvent using the CHARMM force field with explicit solvent [24].

From the optimized molecular structures, we estimated the probe sizes, which were defined as the distance between the oxygen atom of the fluorophore (indicated by the magenta arrows in Author response image 2B and D) and the nitrogen atom of the maleimide group (indicated by the cyan arrows in Author response image 2A and C).

Whilst these components exhibit highly diverse primary and hence macro- and supra-molecular structures, we present evidence that amino acid composition alone may be a useful predictor of age-related protein degradation in both photoexposed and, as a consequence of differential oxidation sensitivity, photoprotected, tissues.

Second, although hyperparameters of the priors are determined from molecular structure databases, we do not train our method using these databases.

Although the chemistry of the process is well established, the role played by molecular structure that we address here with atomistic molecular-dynamics simulations remains controversial.

As described above (see Methods section for 2D molecular structure similarity), we calculated the TC between all the drug pair fingerprints.