Sentence examples for modulate the biophysical from inspiring English sources

Our coarse-grained molecular dynamics study not only reproduces experimentally reported findings but also provides a detailed molecular understanding of the elusive unfolded-state ensemble and how charge charge interactions can modulate the biophysical characteristics of folding.

Small molecule structure correctors of ApoE4 have been suggested that effectively modulate the biophysical properties and the function of abnormal proteins.

Given the relevance of plasmalogen depletion in several neurodegenerative diseases, it is important to understand how plasmalogens modulate the biophysical features of lipid membranes.

Glycans modulate the biophysical properties of proteins and lipids and play particularly prominent roles in cellular interactions as the primary constituents of the often nanometer thick glycocalyces coating all mammalian cells.

Interestingly, GD3 – which can modulate the biophysical properties of membrane raft assemblies similar to GM3 (and in essence serves as a reservoir for this monosialylated ganglioside, Figure 7A) – was also reduced by SMF; this result can be explained by the ability of NEU3 to remove both sialic acid residues of GD3.

The recent work on the engineered SH3 domain variants also clearly suggested that glycosylation can enrich as well as modulate the biophysical properties of proteins and could, in fact, be used as an alternative way to design thermally stabilized proteins [ 30].

In addition, it has been described that oxidized cardiolipin modulates the biophysical properties of MOM to allow oligomerized BAX to insert and permeabilize the MOM [63, 65, 66].

Moreover, polymorphism V1951L found in Latinos also modulates the biophysical effects of SCN5A mutations, and has been identified in a victim of SIDS.

With respect to this idea, it is known that most ion channels exist as heteromultimeric protein complexes in which binding partners modulate the transport and the biophysical properties of the pore-forming subunit (Levitan, 2006).

Biomimetic systems can be engineered to incorporate extrinsic biochemical and biophysical signals to modulate the stem cell niche, to control cell-cell and cell-matrix interaction, oxygen distribution, local pH levels and nutrient transport within organoids (Yin et al., 2016).

SP-A performs host defense activities and modulates the biophysical properties of surfactant in concerted action with surfactant protein B (SP-B).