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Regardless of the structure, the orientation of β subunit is critical for its ability to regulate the biophysical properties of α12.2 channels.
Our study represents the first comprehensive analysis of a family of ion channels in an avian genome and identifies molecular components that likely regulate the biophysical and excitable properties of the song control circuitry.
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Studies with the cloned subunits clearly established the critical roles of the α2δ and β subunits in trafficking and regulating the biophysical properties of the α1 subunit.
One such target, PKA, is well-characterized in regulating the biophysical properties of BK channels.
In addition, the voltage-dependent calcium-channel (cacgn4) gene regulates the biophysical properties of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors (Sager et al., 2009) and secretogranin II (scg2) encodes to a secretory protein and mediates the packaging and sorting of neuropeptides into secretory vesicles (Fischer-Colbrie et al., 2005; Kassahn et al., 2009).
β-Subunits regulate the surface density and the biophysical properties of the channel complex (Shao et al., 2009) and knockout mice lacking β2 subunit show reduced VGSC surface expression (Chen et al., 2002).
Again, the ability of Cavβ subunits to regulate these biophysical properties were totally abolished in the Bdel1 and Bdel3 mutants.
The planetary boundaries framework defines a safe operating space for humanity based on the intrinsic biophysical processes that regulate the stability of the Earth system.
The aim of our study was to identify a potassium channel with the appropriate biophysical attributes to regulate the myometrial resting membrane potential during gestation.
Other than biophysical properties, soluble factors present in the microenvironment can also regulate the activation, proliferation and differentiation of MuSCs.
WHO should regulate the BBC?
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com