Sentence examples for modified by posttranslational from inspiring English sources

Shortly after or even during synthesis, the residues in a protein are often chemically modified by posttranslational modification, which alters the physical and chemical properties, folding, stability, activity, and ultimately, the function of the proteins.

It has been reported that ER-α is modified by posttranslational palmitoylation in the ligand-binding domain that may contribute to its membrane localization [7].

It has been reported that ER is modified by posttranslational palmitoylation in the ligand-binding domain that may contribute to its membrane localization [8].

The N-terminal tails of each histone extend outward through the DNA strand containing amino acid residues modified by posttranslational acetylation, methylation, and phosphorylation.

Class IIa bacteriocins are ribosomally synthesized as inactive prepeptides that are modified by posttranslational cleavage of the N-terminal peptide leader at a double-glycine site in order to release mature and active cationic peptides.

As the processes of transcription and translation of mRNA are controlled at multiple levels, and since the final products (the encoded proteins) can be further modified by posttranslational modifications, it is likely that some of the extrapolations based on mRNA expression might not materialize at the final protein level.

Recently, it has been demonstrated that SREBP1c is dynamically modified by various posttranslational modifications.

Emerging evidence indicates that PAP is modified by various posttranslational modifications, including phosphorylation, acetylation, and sumoylation, which result in important changes in its enzyme activity, nuclear localization, stability, and association with the 3′-processing complex.

Histones are highly basic globular proteins, with N-Terminal "tails" which can be heavily modified by a variety of posttranslational modifications, or histone marks [3].

Additionally, many proteins that enter the ER will be posttranslational modified by glycosylation.

The wide diversity of proteins modified by DSSylation implies that this posttranslational modification might be a fundamental process in biology.