Sentence examples for might directly activate from inspiring English sources

However, given this data, we also considered whether Sall4 might directly activate the Oct4-gfp transgene in the absence of overall reprogramming.

Other data obtained with fibroblasts provide evidence that Egr-1 might directly activate HO-1 [32,33].

Despite the fact that Rbf1/dE2F2 complex is almost exclusively described as a transcriptional repressor, our results suggest that Rbf1 and dE2F2 might directly activate how transcription.

Second, the bacterial components and toxins of H. pylori infection might directly activate the peripheral sensory neurons and enhance the visceral hypersensitivity.

By contrast, the identification of a Foxa1-bound peak downstream of Neurog2 coding sequences (Neurog2 3′) raised the possibility that Foxa2 might directly activate Neurog2 expression through this putative enhancer region in embryonic mDA progenitors (Fig. 2A).

These data imply that Sall3 is activated in Sop-expressing photoreceptors undergoing terminal differentiation, and that Sall3 itself might directly activate a subset of cone-specific genes in a coordinated manner, analogous to the orphan nuclear hormone receptor Errβ (Esrrb) in rod photoreceptors (Onishi et al., 2010b).

One possibility might be that an unopposed activity of ERK in the context of DUSP6 deficiency may directly activate the ATM-CHEK2 signalling.

As Hnf6 has been reported to directly activate Pdx1 early in pancreas development, we predicted we might detect increased levels of Pdx1 in Hnf6 Tg animals on the microarray.

On the other hand, the results of in vitro studies suggest that inhibition of TWEAK by CD163 might have a potential anti-fibrotic effect because, as discussed above, TWEAK can directly activate fibroblast functions [ 19- 21].

Higher concentrations directly activate the receptors.

Alternatively, DISC can also directly activate these effector caspases [6].