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However, thapsigargin, but not Ssd, induced the splicing of Xbp-1 mRNA, whereas only Ssd induced IRE1 (inositol-requiring transmembrane kinase/endonuclease 1 -mediated JNK and caspase 1 -mediatedon, suggesting that Ssd might specifically activate the IRE1-JNK-mediandd apoptoticaspaseay.
The large HBV surface protein and the X protein of genotype C might specifically activate important transcriptional factors in NF-κB-signaling pathways.
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Several observations suggest that the proteolytic activity of Wss1 might be specifically activated in smt3-331 cells.
We review here the most recent research in the genetics of AML and how these discoveries have led, or might lead, to therapies that specifically activate cell death pathways to substantially challenge this 'fearful' disease.
"If we can find drugs that specifically activate those neurons in people, we might be able to have an effect on obesity," Domingos says.
In fact, XFD-1' is a dorsal lip-specific transcription factor, which is specifically activated in Xenopus organizer.
By seeking to understand how STAT3 can function in a diversity of cellular contexts, we might be able to unveil the mechanisms whereby STAT3 specifically activates an anti-inflammatory programme in macrophages and DCs.
The compound shows stability in aqueous media until specifically activated by β-lactamase (βL).
Glucocorticoids induce differentiation of a specifically activated, anti-inflammatory subtype of human monocytes.
OnOr6/2 was specifically activated only by Z11 14 OAc (Figure 2E).
25 genes sets were specifically activated by PDGFRα/β heterodimers.
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