Sentence examples for mice we considered from inspiring English sources

Motivated by the absence of obvious phenotypic defects in adult Prnp0/0 mice, we considered proteins that might overlap functionally with PrPC.

Given the low frequency of intestinal CD4+ ILCs in TRUC mice we considered it unlikely that these cells would play a major role in disease.

Because of both the good predictive performance and the high pairwise correlation of AAWS of healthy BALB/c mice, we considered their average AAWS as representative of healthy BALB/c mice.

Although these studies were performed in mice, we considered it to be extremely unlikely that cytokine gene expression in the hypothalamus or spleen of rats would still be elevated 21 days following LPS.

To first understand the generation of the major subpopulation of CD4+ThPOK− T cells in 4in8 mice, we considered that the transient downregulation of Cd8-encoded CD4 proteins during positive selection would disrupt, albeit transiently, MHCII-specific TCR signalling in CD4-dependent thymocytes (Sarafova et al, 2005, 2009).

As first evaluation of mean of the observed increase in all CA3 isoform protein levels in quadriceps of MDX-Sed mice, we considered the possible positive correlation with an increased need of acid-base balance regulation [ 30] and, based on this point of view, the increased levels of CA3 in mdx muscle should result protective against, e.g. pH change.

While there is a population of cells that are slightly CXCR4+ (CXCR4low) that are present at similar levels in both saline-treated and bleomycin-treated mice, we consider fibrocytes to be the population of CD45+/ColI+/CXCR4high cells in the boxes that are present at much higher levels in bleomycin-treated mice than in saline-treated mice.

In regards to the mechanisms of the laminopathy-based premature aging in the GMF-TG mice, we consider it possible that GMF over-expression in non-brain tissue may cause secondary laminopathy through enhancing oxidative injuries, probably due to its vulnerability to oxidative stress [ 14].

The scenario was the same (and statistically significant when comparing control mice and B-cell-specific Carabin-deficient treated mice) if we considered the highest score of IgG and C3 deposits in renal glomeruli (Table 1, illustrated in Fig 6A).

SWDs correlate with worsened memory performance in APP/PS1 mice, which we considered as a promising feature for a possible surrogate marker of both disease and drug efficacy.

To prepare a tandem duplicate-free mouse genome we considered 19 684 known genes from the LocusLink database that were mapped on the mouse genome assembly (NCBI build 32) [ 57].