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Methodologically good studies were more likely to show statistically significant risks than studies of moderate quality.
Meta-analysis across all methodologically good studies found a statistically significant risk of 1.6 (95%CI 1.3-2.0) for doctors.
Pooling of all methodologically good studies confirmed this increased risk (RR 1.52; 95%CI 1.27-1.81), whereas the methodologically moderate studies provided no evidence of higher risk.
While the studies as a whole and the methodologically good studies showed statistically significant results, the moderate studies showed no difference in H. pylori prevalence between gastroenterological personnel and the controls (Table 3).
If only methodologically good studies are considered, there is no change in the Asian studies, whereas in Europe a statistically significant increase in risk for all personnel can be seen.
Nor can the quality of studies be sufficient reason for this difference, although stratification by study quality did reveal larger effect estimates in methodologically good studies than in those with moderate quality in Europe.
Similar(54)
Methodologically good-quality studies, preferably evaluating results with a validated patient-relevant outcome measure such as the KOOS or WOMAC (Paxton and Fithian 2005), are needed to establish the optimal treatment strategy for patients with isolated patellofemoral osteoarthritis.
Interpretation Methodologically good quality comparative studies, preferably using a patient-relevant outcome instrument, are needed to establish the optimal treatment strategy for patients with isolated patellofemoral osteoarthritis.
Reporting bias was minimised by including all available methodologically sound studies (published or not).
Dr. Judith M. Glassgold, chair of APA's task force, addressed the lack of "methodologically sound studies" in a statement on the group's findings in 2009.
The LBP prevalence data extracted from these methodologically sound studies were analyzed.
Related(16)
methodologically adequate studies
methodologically uniform studies
methodologically similar studies
methodologically heterogeneous studies
methodologically strong studies
methodologically sophisticated studies
methodologically rigorous studies
methodologically weak studies
methodologically sound studies
methodologically robust studies
methodologically flawed studies
methodologically diverse studies
methodologically correct studies
methodologically appropriate studies
methodologically acceptable studies
methodologically good quality studies
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