Sentence examples for methodologically adequate studies from inspiring English sources

Pairs of independent reviewers extracted the key features and prescribing outcomes of methodologically adequate studies (experiments and strong quasi-experiments).

We extracted key features of the characteristics, methods, and outcomes of methodologically adequate studies using a standardized data extraction tool.

Subgroup analyses are presented for methodologically adequate studies, and figures with subgroup summary statistics are presented to demonstrate effects in individual studies and their settings.

Specifically, we aim to describe interventions to improve the quality and efficiency of medication use in the US managed care setting published between July 2001 and January 2007; detail key features of methodologically adequate studies; summarize intervention effects; and identify the most successful types of interventions.

Based on the ability of specific research designs to control adequately for common threats to internal validity [ 8, 11, 12], our definition for methodologically adequate studies included: randomized controlled trials (RCTs); pre-post studies with non-randomized comparison group(s); and interrupted time series analysis with or without comparison group.

Limiting the analyses to studies qualified as methodologically adequate eliminates the heterogeneity, as it reduces the analyses to one study (n = 1000).

On the other hand, since the course of CFS is highly fluctuating, with alternating periods of improvement and deterioration, it has been recommended that any therapeutic modality should comply with several requirements to consider the study as methodologically adequate.

Limiting the analyses to studies qualified as methodologically adequate reduces the heterogeneity to marginally significant (P= 0.06), and confirms the effect of misoprostol on reducing PPH compared with expectant management (OR 0.63, 95% CI 0.41 0.99, two studies, n = 2281); both studies were conducted in rural areas of developing countries.

Similarly, oxytocin substantially but not significantly lowered severe PPH in the two studies conducted in developing countries, both of which were quasi-experimental (and thus did not qualify as methodologically adequate) (OR 0.42, 95% CI 0.04 4.81; two studies, n = 5203).

The only methodologically adequate trial (n=55) 71 did not report any clinical relapses during hospitalisation, without longer follow-up.

To our knowledge only few studies have been designed in a (methodologically) adequate way to make any assumptions about this relation [ 77, 79, 80].